Trimetazidine
Trimetazidine is an anti-ischemic anti-anginal metabolic agent of the fatty acid oxidation inhibitor class meaning that it improves myocardial glucose utilization through. It works by producing a good supply of oxygen for the cells of the heart.
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Trimetazidine is a fatty acid oxidation inhibitor used to prevent and treat the symptoms of angina or chest pain that is the result of a lack of blood supply and oxygen to the heart.
. Trimetazidine is a drug for angina pectoris sold under many brand names. Trimetazidine has been studied as a treatment for angina pectoris since the late 1960s. This medicine is used when patients do not respond adequately to other agents or are intolerant to first line anti-anginal agents.
Trimetazidine is a piperazine derivative indicated for the symptomatic treatment of stable angina pectoris in patients inadequately controlled or intolerant to first line therapies. Trimetazidine is used for the treatment of chest tightness medically known as angina pectoris. Trimetazidine is described as the first cytoprotective anti-ischemic agent developed and marketed by Laboratoires Servier France.
Trimetazidine a piperazine compound is an antianginal drug widely used in France and belongs to the group of partial fatty acid oxidation inhibitors so-called PFox inhibitors. It inhibits the long-chain mitochondrial 3-ketoacyl coenzyme A thiolase enzyme in the mitochondria resulting in the improvement of mitochondrial metabolism through inhibition of myocardial fatty acid uptake and oxidation and consequent stimulation of. Trimetazidine has cardioprotective effects in animal models of ischemia156 In clinical trials of chronic stable angina pectoris trimetazidine was as.
17 hours agoTrimetazidine is a performance-enhancing drug long connected to doping in sports. Acidic conditions caused by anaerobic metabolism and fatty acid oxidation in response to myocardial ischemia activate. Trimetazidine is used in the treatment of Angina heart-related chest pain.
Trimetazidine is an anti-ischemic agent widely used in the treatment of coronary artery disease. It is banned but has popped up in the news during the course of the 2022. Trimetazidine is used in combination with other drugs for the symptomatic treatment of stable angina pectoris chest pain caused by decreased oxygen supply due to reduced blood flow to the heart.
This medicine also prevents a sudden rise in blood pressure and also helps in reducing the frequency of angina attacks. The medicine also slows the beta-oxidation of fatty. 17 hours agoTrimetazidine also known as TMZ is a drug used to treat the heart condition angina so it might seem strange that its currently at the heart of a possible doping situation at the 2022 Olympics.
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